Understanding The Organ/Tissue Procurement Process

http://www.kidney.org/general/news/procurementfacts.cfm

 

Deciding about organ and tissue donation usually comes after a sudden and unexpected death, an emotionally traumatizing time. Trying to comprehend the organ/tissue procurement process at that time can be very difficult due to the overwhelming emotions that occur. This can lead to confusion, or even suspicion, which may be why some families decline to donate the organs/tissues of their loved ones. The National Kidney Foundation wants to help educate the public about the process to alleviate the myths and misconceptions surrounding organ donation, thereby increasing donation to help the more than 55,000 people waiting for life-saving organ transplants and the 400,000 more that benefit each year from tissue and cornea donation. This fact sheet is designed to outline the process that usually occurs (though each experience may be somewhat different depending on the circumstances). We encourage families to discuss the issue of organ/tissue donation and make their wishes known.

The procurement process is a complex series of events that involves medical professionals at all levels in varied settings. Federal and state legislation has been enacted to help ensure that the process is carried out in a fair and efficient way, leading to an equitable distribution of donated organs. This legislation recommended the establishment of a national computer registry, called the National Organ Procurement and Transplantation Network (OPTN), for the purpose of matching donor organs to waiting recipients. The OPTN is managed by an organization known as the United Network for Organ Sharing (UNOS), located in Richmond, Virginia. UNOS cooperates with regional organ procurement organizations throughout the country to place organs locally, regionally and nationally. Here's how the process works:

  1. The hospital identifies a potential donor. This may be done by an attending or consulting physician, donor coordinator, house supervisor, emergency room or intensive care unit nurse. An individual who is brain dead but is on a respirator and has a beating heart is an acceptable donor for: heart, liver, pancreas, eyes/corneas, kidneys, intestine, heart valves, skin, bone and lungs. An individual who has died due to a cardiac arrest and has no cardiac or respiratory activity is an acceptable donor for: eyes/corneas, blood vessels, cartilage, skin, bone, pericardium, and soft tissues. Other criteria for potential organ and tissue donors include certain age limits and the absence of unresolved systemic infections or extra-cerebral malignancies.
  2. The hospital contacts the local organ procurement organization (OPO) to assess the potential donor's status and confirm his or her suitability.
  3. A physician declares brain death. This must be done in accordance with state law, preferably by an neurosurgeon or neurologist.
  4. A medical evaluation of the potential donor is conducted by a representative of the organ procurement organization or an in-house donor coordinator. This includes a complete history and physical examination of the potential donor.
  5. The potential donor's next-of-kin are asked to sign a donor consent form. Most states have passed "required request" laws, which make it mandatory for the hospital to offer the family the option of donating their deceased loved one's organs and tissues. Some states have what is called "required referral" laws which require the hospital to notify the OPO of all deaths, and if appropriate, in collaboration with the OPO, to advise the family of their right to donate.
  6. The donor is maintained medically by a representative of the organ procurement organization, the in-house coordinator or the nurse in the unit after brain death has been declared.
  7. The donor coordinator arranges the arrival and departure times of the surgical transplant teams and schedules the operating room time. The surgical team consists of surgeons and operating room clinician or organ/tissue preservationist.
  8. When the surgical team arrives, the donor is taken to surgery. A complete operating room staff should be available for multiple organ retrieval. A special surgical team is usually required for removal of heart, liver, lungs and pancreas; kidneys may be removed either by local surgeons or by a special team.
  9. Disposition of the body takes place according to the guidelines of the hospital. There is no change in the body's appearance after organ and tissue donation, and open-casket funerals are still possible.
  10. The organs are matched to potential recipients. Tissue typing takes about 6 hours. This testing is done for all kidney transplants, is recommended for pancreas transplants and may be required for other types of transplants. UNOS has developed a point system for selecting recipients as objectively as possible. In addition to the tissue type and blood group, other criteria include: percent of reactive antibody, waiting time on the list, medical urgency, and, in the case of liver and heart transplants, distance from the transplant center.
  11. Once the recipients have been identified, they are called in for their preoperative workups.
  12. The donor coordinator/preservationist sends the organs and/or tissues to the institution where preservation or the transplant will take place.
  13. The selected individuals are taken to surgery and the transplants are performed.
  14. The procurement organization takes care of follow-up, which may include letters to the donor family, staff physician and nurses, regarding the transplanted organs and/or tissues.

While the procurement process is well-organized and efficiently run, it cannot be fully successful as long as the shortage of donated organs and tissues persists. Through its Organ Donor Program, the National Kidney Foundation is striving to reverse these shortages through special programs and annual public information campaigns, such as National Organ and Tissue Donor Awareness Week, the U.S. Transplant Games, National Donor Family Council, transAction Council and Making the Critical Difference, an educational program for critical care nurses.